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Key Targeted Gene Editing    

CRISPR/Cas9 gene editing technology brings a DNA editing revolution, which is faster, more accurate, less cost and has a wide range of potential applications than previous DNA editing techniques. Geneticists and medical researchers can use CRISPR/Cas9 technology to quickly delete, insert, or alter a portion of a DNA sequence. Guided by gRNA, Cas9 targets specific sites in the DNA and forms a double-stranded break (DSB). During DSB repair, one or more genetic changes are introduced through the non-homologous end joining (NHEJ) or homology directed repair (HDR, repair template required) pathway.

CRISPR PlatformCB, one of the leading gene editing technology companies, is specializing in CRISPR/Cas9 gene editing services. Based on our professional scientists' team and national-class labs, we have been successfully implemented hundreds of genes deletion in cells and mice using CRISPR/Cas9 technology (Table 1). We use optimized gene targeting strategies to achieve the most efficient gene editing efficiency, and we provide you with one-stop gene editing services, including designing gene editing strategies for the final cell line or model animal. To meet your research needs, we offer CRISPR/cas9 knockout, knock-in, point mutation, conditional knockout cell lines and animal models, etc.

Key Targeted Gene

ABCA1CCR5CSF1RFGF2IL-2NOS2SST
ABCC1CD160CSKFGF21IL-2RANotch2STAT3
ABCC3CD19CTCFLFGFR1IL-3RANotch3STAT6
ABL1CD22CTGFFGFR2IL-4NOX3Syk
ACE2CD248CTLA-4FGFR3IL-4RPARP1TAT
ADACD27CXCR1FGFR4IL-6PARP2TBK1
AhRCD276CXCR2FLT1IL-6RPARP3TERT
AKT1CD28CXCR3FLT3IL-8PCNATF
AKT2CD33CXCR4FOXC2IL-9RPD1TGFB1
AKT3CD37CXCR7FSHRIRAK4PDE10ATLR3
ALDH2CD3eCYP17A1FynITKPDK1TLR4
ALKCD4CYP19A1GAS-6JAK1PECAM-1TLR5
ApoBCD40CYP2A6GDF-2JAK2PIGFTLR7
ApoECD44DDR1GHRJAK3Pim1TLR8
ARCD47DDR2GLP1RKAAG1Pim2TLR9
ARL-1CD52DHFRGLSKIR-2DL1Pim3TNIK
ARVCFCD70DHODHGnRH1KIR-2DL2PKMTP53
ATF-5CD74DKK1GnRH-RKIR-2DL3PLK-1TRPA1
ATMCD79BDLL1GPRC5DKIR-3DL2PollTrpC5
ATRAIDCD80DLL3GRB2LAG-3PRAMETrpV1
AXLCD86DLL4GRP-RLCKPRF1 TRPV2
Bcl2CD9DNMT1GSTP1LDLRPRLTSH-R
Bcl-2A1CDC7eEF1A-2GZMBLRRK2PRLRTyk2
BcrCDK1EGFHDAC1Ly-75PRMT5UCH-L5
BrafCDK2EGFRHDAC2LYNPROX1USP14
BMP-10CDK3ENGHDAC3MAP3K9PTENVCAM-1
BMXCDK4Ep-CAMHDAC6MARCKSPTK7VCP
Brd2CDK5EphA2HDAC10MC1-RRAD51VDR
Brd3CDK6EphA3HDAC11MCL1RanVIP
Brd4CDK7EphB4HGFMDM2RETWee1/2
BTKCDK8EphB6HIF1AMdm4ROBO4WNT5A
CACDK9ERBB2HK2MECOMROR1WT1
CA2CDK12EZH2HPSEMELKSEMA-4DXIAP
CA3CDK19FABP4HSF1MERTKSHE
cAMPCEACAM5FAP-αHSPB1METSLAMF7
CCKA-RCEBPAFASIGF1MGMTSLC6A8
CCKB-RCFTRFASLGIGF1RMIFSMO
CCR2CLUFASNIGF2MSl1SOD1
CCR4CRBNFGF1IL-13RA2mTORSrc

If you don't see the gene you are interested, please don't hesitate to contact us. CRISPR PlatformCB will provide you customized CRISPR/Cas9 gene editing services for your target genes. Tell us about your needs, we guarantee our clients the most reliable and efficient services to best match your research goals, with the shortest turnaround time and the most reasonable price.

For research use only. Not intended for any clinical use.
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