SpCas9 Nuclease (+NLS)

CCP-002

This product is the recombinant Streptococcus pyogenes Cas9 nuclease fused with NLS at N-terminal which is purified from E.coli. The spCas9 nuclease can be used for gene editing by inducing double-strand breaks in genomic DNA. Combining with guide RNA, spCas9 targets to specific site of genome and leads to DNA breaks within 3 bases from the NGG PAM (Protospacer Adjacent Motif).

Gene editing (KO/KI/Point Mutation cell line generation)

Dry ice package

Store at -80°C