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Fragile X syndrome is the most common cause of mental disability in men. One out of every 3,600 boys born is affected. This syndrome can also lead to autism, such as social & communication barriers, and attention & hyperactivity problems. At present, this disease can not be cured.
Hundreds of millions of years ago, plant and animal genomes were littered with viral DNA debris. So far, it has generally been assumed that most of the virus residues integrated into the plant and animal genomes are inactive. But in January 11th, two Cell articles confirmed that some of them might have evolved into the genes that promoted cellular communication by Drosophila and mice experiments.
In the period of infection or tumor growth, a special white blood cell named CD8+T rapidly reproduces in spleen and lymph node, and obtains the ability to kill normal cells of diseased patients. Then these "killers" fully equip themselves for the place where they are needed.
What is man? Is life meaningful? Where will man go?
Things must be put together neatly; check several times whether the door is locked or not before going out... I believe that everyone has such a friend around us. We generally call this behavior "obsessive-compulsive disorder". It is estimated that more than 80 million people around the world suffer from obsessive-compulsive disorder, many of whom develop involuntary obsessive thinking and make repetitive behaviors that are difficult to be understood by outsiders.
"Light shines, and the tumor shrink". It may sound like a science fiction, or the way of exaggerating thing. But in fact, this is the result after careful study by researchers from the Rochester College. They applied a very novel and effective weapon—optogenetics into the field of cancer immunotherapy, effectively alleviating the immune inhibition in solid tumor micro-environment and minifying the tumor significantly.
An international team led by KAUST found an epigenetic mechanism for regulating gene activity in the study of the adult genomes and their interactions with environment.
In a new study, researchers from the Karolinska Institute in Sweden mapped how different DNA-binding proteins in human cells respond to certain biochemical modifications of DNA molecules. They reported that some of the major regulatory proteins were able to activate regions of the genome that were not active in the normal case due to epigenetic changes. Their findings helped better understand the process of gene regulation, embryonic development and diseases leading to cancer. The results of the study were published in the Science on May 5, 2017, entitled "Impact of cytosine methylation on DNA binding specificities of human transcription factors".
