Our promise to you:
Guaranteed product quality, expert customer support.
24x7 CUSTOMER SERVICE
CONTACT US TO ORDER
Custom Viral Service
Brief Introduction
Creative Biogene provides world-class packaging services for a variety of viral types using our QVirusTM platform. Creative Biogene's state-of-the-art facilities and highly experienced staff are available in order to assist in all areas of virus vector design and construction, as well as the generation of the virus in a quick turnaround. Our custom viral services are highlighted by a consistent high titer and large delivery viral counts.
Viral vectors are a tool commonly used by molecular biologists to deliver genetic material into cells. This process can be performed inside a living organism (in vivo) or in cell culture (in vitro). Though a number of viruses have been developed, interest has centered on four types: retrovirus, lentivirus, adenovirus and adeno-associated virus (AAV).
Comparison of adenovirus, AAV, retrovirus and lentivirus for gene delivery
| Features | Adenovirus | AAV | Lentivirus | Retrovirus |
| Genome | dsDNA | ssDNA | ssRNA | ssRNA |
| Infect Dividing Cells | Yes | Yes | Yes | Yes |
| Infect Non-dividing Cells | Yes | Yes | Yes | No |
| Genomic Integration | No | Yes/No | Yes/No | Yes |
| Expression Pattern | 10 days to months | 2.5–6.0 months | >12 months | Days to months |
| Expression Level | High | Moderate | Moderate | Moderate |
| Cloning Capacity | 8-30 kb | 3.5–4.0 kb | 7–8 kb | 7–8 kb |
| Immune Response | High | Very low | Low | Moderate |
| Viral Titer | High | Moderate | Moderate | Moderate |
| Transduction Efficiency | High | Moderate | Moderate | Moderate |
Features of Creative Biogene's viral packaging services
- Quality: Production of virus in a state-of-the art BSL-2 facility with robust quality control in accordance with NIH Biosafety Level 2 criteria.
- High Titer: Using proprietary technologies that are unique and highly efficient, we can easily yield 108 to 109 TU/ml lentivirus/retrovirus without concentrating steps.
- Quick Turnaround: Creative Biogene has consolidated its procedure of viral packaging services as a standard production-line resulting in a quick turnaround.
- Service Customization: We will do anything in our power to make sure your needs are met. We offer plasmid amplification, custom vector building, and large scale production.