Creative Biogene
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Microbe Genome Editing Service

Brief Introduction


Creative Biogene offers the best services in the field of microbe genome editing which help to add new functions or to optimize an existing bioprocess. With a lot of talent scientists and technicians, Creative Biogene has built an excellent and mature platform to modify a series of different microbes. In addition, we will also save your time and cost of the microbe genome modification programs by taking advantage of our expertise and innovative technology platforms.

By engineering and optimizing genetic coding to regulatory processes in microbes, Creative Biogene could increase the yield of key compounds, such as chemicals, and proteins for pharmaceutical and nutraceutical ingredient development. A broad range of microorganisms, such as E. coli, S. cerevisiae, and others, which could be edited precisely by Creative Biogene, are popular cell sources for above molecules in industry field.

Microorganisms have been used for the production of fermented food products, such as cheese, sourdough, beer, wine, and vinegar. By transforming raw materials to value-added products with superior flavor, texture, and longevity, humans have enjoyed the benefits of this biotechnology. Microorganisms genome editing can optimize the metabolic pathways and phenotypes of the most familiar industrial microorganisms, greatly improve the production traits of the strains and shorten the breeding cycle. At present, a lot of technologies have been used in the transformation and improvement of industrial microbial strains, showing a good application prospects in the process of breeding strains. In addition, microorganisms genome editing has also been widely applied in pharmaceutical and environmental.

Creative Biogene provides two different platforms for microbe genome editing service, including traditional recombineering system and CRISPR/Cas 9 system.

The Schematic of Recombineering and CRISPR/Cas 9 system Fig.1 The Schematic of Recombineering and CRISPR/Cas 9 system

Advantages of microbial gene editing in Creative Biogene:

  1. A wide range of microorganisms species
  2. Scarless genome editing
  3. Precise editing to every base pair
  4. Fast and high efficiency

There are a lot of applications in microbial gene editing, including but not limited to the following items:

  1. Industrial Applications
  2. Pharmaceutical applications
  3. Environmental applications
  4. Agricultural applications

Creative Biogene offers a large panel of microorganisms' genome editing services. Our excellent staffs with abundant project experience and professional know-how, will work together with you closely and report the project progress in time. Creative Biogene has confidence in speeding your microbe genome editing project and delivering the final products with fast turnaround time and high-quality.

If you have any special requirements in our microbe genome editing service, please feel free to contact us. We are looking forward to working together with your attractive projects.

Publications
  1. Fekete F J, Marotta N J, Liu X, et al. An O2-sensing diguanylate cyclase broadly affects the aerobic transcriptome in the phytopathogen Pectobacterium carotovorum[J]. Frontiers in Microbiology, 2023, 14.
For research use only. Not intended for any clinical use.
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